diff --git a/bin/tests/system/cipher-suites/tests_cipher_suites.py b/bin/tests/system/cipher-suites/tests_cipher_suites.py
index edc3c09598..86adc29da1 100644
--- a/bin/tests/system/cipher-suites/tests_cipher_suites.py
+++ b/bin/tests/system/cipher-suites/tests_cipher_suites.py
@@ -9,7 +9,7 @@
 # See the COPYRIGHT file distributed with this work for additional
 # information regarding copyright ownership.
 
-import re
+from re import compile as Re
 
 import pytest
 
@@ -31,7 +31,7 @@ pytestmark = pytest.mark.extra_artifacts(
 @pytest.fixture(scope="module")
 def transfers_complete(servers):
     for zone in ["example", "example-aes-128", "example-aes-256", "example-chacha-20"]:
-        pattern = re.compile(
+        pattern = Re(
             f"transfer of '{zone}/IN' from 10.53.0.1#[0-9]+: Transfer completed"
         )
         for ns in ["ns2", "ns3", "ns4", "ns5"]:
diff --git a/bin/tests/system/configloading/tests_configloading.py b/bin/tests/system/configloading/tests_configloading.py
index de3d25aa71..ec017a8bfe 100644
--- a/bin/tests/system/configloading/tests_configloading.py
+++ b/bin/tests/system/configloading/tests_configloading.py
@@ -9,8 +9,7 @@
 # See the COPYRIGHT file distributed with this work for additional
 # information regarding copyright ownership.
 
-import re
-
+from re import compile as Re
 
 import isctest
 
@@ -59,7 +58,7 @@ def test_reload_fails_log(ns1, templates):
         "apply_configuration",
         "loop exclusive mode: starting",
         "apply_configuration: configure_views",
-        re.compile(r".*port '9999999' out of range"),
+        Re(r".*port '9999999' out of range"),
         "apply_configuration: detaching views",
         "loop exclusive mode: ending",
         "reloading configuration failed",
diff --git a/bin/tests/system/conftest.py b/bin/tests/system/conftest.py
index bbb2c28385..9eff2ee8b2 100644
--- a/bin/tests/system/conftest.py
+++ b/bin/tests/system/conftest.py
@@ -12,7 +12,7 @@
 import filecmp
 import os
 from pathlib import Path
-import re
+from re import compile as Re
 import shutil
 import subprocess
 import tempfile
@@ -53,7 +53,7 @@ else:
 
 XDIST_WORKER = os.environ.get("PYTEST_XDIST_WORKER", "")
 FILE_DIR = os.path.abspath(Path(__file__).parent)
-ENV_RE = re.compile(b"([^=]+)=(.*)")
+ENV_RE = Re(b"([^=]+)=(.*)")
 PRIORITY_TESTS = [
     # Tests that are scheduled first. Speeds up parallel execution.
     "rpz/",
@@ -62,9 +62,9 @@ PRIORITY_TESTS = [
     "timeouts/",
     "upforwd/",
 ]
-PRIORITY_TESTS_RE = re.compile("|".join(PRIORITY_TESTS))
-SYSTEM_TEST_NAME_RE = re.compile(f"{SYSTEM_TEST_DIR_GIT_PATH}" + r"/([^/]+)")
-SYMLINK_REPLACEMENT_RE = re.compile(r"/tests(_.*)\.py")
+PRIORITY_TESTS_RE = Re("|".join(PRIORITY_TESTS))
+SYSTEM_TEST_NAME_RE = Re(f"{SYSTEM_TEST_DIR_GIT_PATH}" + r"/([^/]+)")
+SYMLINK_REPLACEMENT_RE = Re(r"/tests(_.*)\.py")
 
 # ----------------------- Global requirements ----------------------------
 
diff --git a/bin/tests/system/dnssec/tests_signing.py b/bin/tests/system/dnssec/tests_signing.py
index b0295e5840..2a1abd531d 100644
--- a/bin/tests/system/dnssec/tests_signing.py
+++ b/bin/tests/system/dnssec/tests_signing.py
@@ -12,6 +12,7 @@
 from collections import namedtuple
 import os
 import re
+from re import compile as Re
 import struct
 import time
 
@@ -475,7 +476,7 @@ def test_offline_ksk_signing(ns2):
         os.rename(f"ns2/{KSK}.private.bak", f"ns2/{KSK}.private")
 
     def loadkeys():
-        pattern = re.compile(f"{zone}/IN.*next key event")
+        pattern = Re(f"{zone}/IN.*next key event")
         with ns2.watch_log_from_here() as watcher:
             ns2.rndc(f"loadkeys {zone}", log=False)
             watcher.wait_for_line(pattern)
diff --git a/bin/tests/system/dnssec/tests_tat.py b/bin/tests/system/dnssec/tests_tat.py
index 609f110c59..e37644f3a9 100644
--- a/bin/tests/system/dnssec/tests_tat.py
+++ b/bin/tests/system/dnssec/tests_tat.py
@@ -10,7 +10,7 @@
 # information regarding copyright ownership.
 
 import os
-import re
+from re import compile as Re
 
 from dns import edns
 
@@ -67,7 +67,7 @@ def test_tat_queries(ns1, ns6):
     msg = isctest.query.create(".", "DNSKEY")
     opt = edns.GenericOption(14, b"\xff\xff")
     msg.use_edns(edns=True, options=[opt])
-    pattern = re.compile("trust-anchor-telemetry './IN' from .* 65535")
+    pattern = Re("trust-anchor-telemetry './IN' from .* 65535")
     with ns1.watch_log_from_here() as watcher:
         res = isctest.query.tcp(msg, "10.53.0.1")
         watcher.wait_for_line(pattern)
@@ -79,7 +79,7 @@ def test_tat_queries(ns1, ns6):
     opt1 = edns.GenericOption(14, b"\xff\xff")
     opt2 = edns.GenericOption(14, b"\xff\xfe")
     msg.use_edns(edns=True, options=[opt2, opt1])
-    pattern = re.compile("trust-anchor-telemetry './IN' from .* 65534")
+    pattern = Re("trust-anchor-telemetry './IN' from .* 65534")
     with ns1.watch_log_from_here() as watcher:
         res = isctest.query.tcp(msg, "10.53.0.1")
         isctest.check.noerror(res)
diff --git a/bin/tests/system/dnssec/tests_validation_multiview.py b/bin/tests/system/dnssec/tests_validation_multiview.py
index 085f388b2c..015e458349 100644
--- a/bin/tests/system/dnssec/tests_validation_multiview.py
+++ b/bin/tests/system/dnssec/tests_validation_multiview.py
@@ -10,7 +10,7 @@
 # information regarding copyright ownership.
 
 import os
-import re
+from re import compile as Re
 
 import isctest
 
@@ -47,7 +47,7 @@ def test_staticstub_delegations():
 
 def test_validator_logging(ns4):
     # check that validator logging includes the view name with multiple views
-    pattern = re.compile("view rec: *validat")
+    pattern = Re("view rec: *validat")
     with ns4.watch_log_from_start() as watcher:
         msg = isctest.query.create("secure.example", "NS")
         isctest.query.tcp(msg, "10.53.0.4")
diff --git a/bin/tests/system/isctest/kasp.py b/bin/tests/system/isctest/kasp.py
index 2e1b2c36fb..f46ceabe73 100644
--- a/bin/tests/system/isctest/kasp.py
+++ b/bin/tests/system/isctest/kasp.py
@@ -15,6 +15,7 @@ import glob
 import os
 from pathlib import Path
 import re
+from re import compile as Re
 import time
 from typing import Dict, List, Optional, Tuple, Union
 
@@ -1475,7 +1476,7 @@ def next_key_event_equals(server, zone, next_event):
         waitfor = rf".*zone {zone}.*: next key event in (?!3600$)(.*) seconds"
 
     with server.watch_log_from_start() as watcher:
-        watcher.wait_for_line(re.compile(waitfor))
+        watcher.wait_for_line(Re(waitfor))
 
     # WMM: The with code below is extracting the line the watcher was
     # waiting for. If WatchLog.wait_for_line()` returned the matched string,
diff --git a/bin/tests/system/isctest/log/watchlog.py b/bin/tests/system/isctest/log/watchlog.py
index 6d85e9817d..d2d8521ebd 100644
--- a/bin/tests/system/isctest/log/watchlog.py
+++ b/bin/tests/system/isctest/log/watchlog.py
@@ -14,6 +14,7 @@ from typing import Any, Iterator, List, Match, Optional, Pattern, TextIO, TypeVa
 import abc
 import os
 import re
+from re import compile as Re
 import time
 
 
@@ -213,7 +214,7 @@ class WatchLog(abc.ABC):
             if isinstance(string, Pattern):
                 patterns.append(string)
             elif isinstance(string, str):
-                pattern = re.compile(re.escape(string))
+                pattern = Re(re.escape(string))
                 patterns.append(pattern)
             else:
                 raise WatchLogException(
@@ -256,13 +257,14 @@ class WatchLog(abc.ABC):
         Recommended use:
 
         ```python
+        from re import compile as Re
         import isctest
 
         def test_foo(servers):
             with servers["ns1"].watch_log_from_start() as watcher:
                 watcher.wait_for_line("all zones loaded")
 
-            pattern = re.compile(r"next key event in ([0-9]+) seconds")
+            pattern = Re(r"next key event in ([0-9]+) seconds")
             with servers["ns1"].watch_log_from_here() as watcher:
                 # ... do stuff here ...
                 match = watcher.wait_for_line(pattern)
@@ -321,7 +323,8 @@ class WatchLog(abc.ABC):
         >>> # Different values must be returned depending on which line is
         >>> # found in the log file.
         >>> import tempfile
-        >>> patterns = [re.compile(r"bar ([0-9])"), "qux"]
+        >>> from re import compile as Re
+        >>> patterns = [Re(r"bar ([0-9])"), "qux"]
         >>> with tempfile.NamedTemporaryFile("w") as file:
         ...     print("foo bar 3", file=file, flush=True)
         ...     with WatchLogFromStart(file.name) as watcher:
@@ -443,7 +446,8 @@ class WatchLog(abc.ABC):
         >>> assert ret[1].group(0) == "foo"
 
         >>> import tempfile
-        >>> bar_pattern = re.compile('bar')
+        >>> from re import compile as Re
+        >>> bar_pattern = Re('bar')
         >>> patterns = ['foo', bar_pattern]
         >>> with tempfile.NamedTemporaryFile("w") as file:
         ...     print("bar", file=file, flush=True)
diff --git a/bin/tests/system/isctest/vars/openssl.py b/bin/tests/system/isctest/vars/openssl.py
index 19d62d1811..3d1829e723 100644
--- a/bin/tests/system/isctest/vars/openssl.py
+++ b/bin/tests/system/isctest/vars/openssl.py
@@ -10,7 +10,7 @@
 # information regarding copyright ownership.
 
 import os
-import re
+from re import compile as Re
 from typing import Optional
 
 from .. import log
@@ -30,7 +30,7 @@ def parse_openssl_config(path: Optional[str]):
         return
     assert os.path.isfile(path), f"{path} exists, but it's not a file"
 
-    regex = re.compile(r"([^=]+)=(.*)")
+    regex = Re(r"([^=]+)=(.*)")
     log.debug(f"parsing openssl config: {path}")
     with open(path, "r", encoding="utf-8") as conf:
         for line in conf:
diff --git a/bin/tests/system/multisigner/tests_multisigner.py b/bin/tests/system/multisigner/tests_multisigner.py
index c356595afe..900cc7e7b4 100644
--- a/bin/tests/system/multisigner/tests_multisigner.py
+++ b/bin/tests/system/multisigner/tests_multisigner.py
@@ -12,6 +12,7 @@
 from datetime import timedelta
 import os
 import re
+from re import compile as Re
 
 import pytest
 
@@ -103,9 +104,7 @@ def check_no_dnssec_in_journal(server, zone):
     ]
 
     cmd = isctest.run.cmd(journalprint)
-    pattern = re.compile(
-        r"^\s*(?:\S+\s+){4}(NSEC|NSEC3|NSEC3PARAM|RRSIG)", flags=re.MULTILINE
-    )
+    pattern = Re(r"^\s*(?:\S+\s+){4}(NSEC|NSEC3|NSEC3PARAM|RRSIG)", flags=re.MULTILINE)
     match = pattern.search(cmd.out)
     assert not match, f"{match.group(1)} record found in journal"
 
diff --git a/bin/tests/system/xfer-servers-list/tests_xfer_servers_list.py b/bin/tests/system/xfer-servers-list/tests_xfer_servers_list.py
index 612be36b1d..54cf2fcaf2 100644
--- a/bin/tests/system/xfer-servers-list/tests_xfer_servers_list.py
+++ b/bin/tests/system/xfer-servers-list/tests_xfer_servers_list.py
@@ -9,7 +9,7 @@
 # See the COPYRIGHT file distributed with this work for additional
 # information regarding copyright ownership.
 
-import re
+from re import compile as Re
 
 import isctest
 
@@ -32,7 +32,7 @@ def wait_for_initial_xfrin(ns):
 
 
 def wait_for_sending_notify(ns1, ns, key_name):
-    pattern = re.compile(
+    pattern = Re(
         f"zone test/IN: sending notify to {ns.ip}#[0-9]+ : TSIG \\({key_name}\\)"
     )
     with ns1.watch_log_from_start() as watcher:
diff --git a/bin/tests/system/xferquota/tests_xferquota.py b/bin/tests/system/xferquota/tests_xferquota.py
index a4edc5998f..a0d042d135 100644
--- a/bin/tests/system/xferquota/tests_xferquota.py
+++ b/bin/tests/system/xferquota/tests_xferquota.py
@@ -12,6 +12,7 @@
 import glob
 import os
 import re
+from re import compile as Re
 import shutil
 import signal
 import time
@@ -71,7 +72,7 @@ def test_xferquota(named_port, ns1, ns2):
         isctest.check.rrsets_equal(ns1response.answer, ns2response.answer)
 
     query_and_compare(axfr_msg)
-    pattern = re.compile(
+    pattern = Re(
         f"transfer of 'changing/IN' from 10.53.0.1#{named_port}: "
         f"Transfer completed: .*\\(serial 2\\)"
     )